My queries keep failing or returning only literature summaries

What this article covers This article explains why K-Pro queries may fail or fall back to literature summaries, and provides guidance on how to write prompts that yield multi-omics analysis results.

Why does this happen?

• The query intent is ambiguous — if K-Pro cannot clearly map your question to a dataset and analysis type, it may return a literature-based answer instead of running a data analysis.
• The requested data is not available in your instance — for example, querying a cancer indication not included in your subscription scope.
• A temporary service issue — the underlying analysis services can experience intermittent errors.

How to write better prompts

Be as specific as possible about the dataset, the analysis type, and the biological entities involved.

Good prompt examples:

• "Plot EGFR expression in lung adenocarcinoma patients from TCGA"
• "Compare survival outcomes for high vs. low CD8+ T-cell infiltration in TCGA breast cancer"
• "Show the spatial distribution of CD36 expression in GBM samples from MOSAIC"

Prompts that may trigger fallback to literature:

• "Tell me about EGFR" → too vague, no dataset or analysis specified
• "What happens in lung cancer?" → general question, likely routed to literature

What to do if errors persist

1. Try rephrasing your query using the examples above.
2. Check the data availability for the indication or dataset you are querying (see Article 2).
3. Wait a few minutes and retry — intermittent service errors often resolve automatically.
4. If the issue persists, submit a support request via the "Need Help" button with the exact prompt and error message.

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