# Preferred ontologies and nomenclatures

The full schemas and data dictionaries of tables used in K-Pro can be provided upon request. Data loaded in K-Pro follows a OMOP like schema with the following notable categorical standards :

| Category Type                        | Possible Values                                                                                                                                                                            |
| ------------------------------------ | ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ |
| QC Status                            | pass \| fail \| flag                                                                                                                                                                       |
| LDH Level Bins                       | Normal \| Elevated \| Low                                                                                                                                                                  |
| Protein Measure Type                 | global \| phospho                                                                                                                                                                          |
| Tumor Region                         | Stroma \| Tumor Edge \| Tumor Islet                                                                                                                                                        |
| Vital Status                         | Alive \| Deceased                                                                                                                                                                          |
| Gender                               | Male \| Female                                                                                                                                                                             |
| ECOG Performance Status              | 0 \| 1 \| 2 \| 3 \| 4 \| 5                                                                                                                                                                 |
| Smoking Status                       | Current \| Former \| Never                                                                                                                                                                 |
| Treatment Response (RECIST)          | Complete Response \| Partial Response \| Stable Disease \| Progressive Disease                                                                                                             |
| Treatment Line                       | Neoadjuvant \| Adjuvant \| First-line \| Second-line \| Third-line                                                                                                                         |
| Treatment Setting                    | Neoadjuvant \| Adjuvant \| Palliative \| Curative                                                                                                                                          |
| Treatment Type                       | chemotherapy \| immunotherapy \| surgery \| radiotherapy \| targeted therapy                                                                                                               |
| Sample Tissue                        | Tumor \| Normal \| Blood \| Metastasis                                                                                                                                                     |
| Histological Sample Type             | Primary Tumor \| Adjacent Normal \| Metastatic \| Recurrent                                                                                                                                |
| Sample Collection Chronology         | Baseline \| On-treatment \| Post-treatment \| Progression                                                                                                                                  |
| TNM T Stage                          | T0 \| T1 \| T1a \| T1b \| T1c \| T2 \| T2a \| T2b \| T3 \| T3a \| T3b \| T4 \| T4a \| T4b \| Tx \| Tis                                                                                     |
| TNM N Stage                          | N0 \| N1 \| N1a \| N1b \| N1c \| N2 \| N2a \| N2b \| N2c \| N3 \| N3a \| N3b \| Nx                                                                                                         |
| TNM M Stage                          | M0 \| M1 \| M1a \| M1b \| M1c \| Mx                                                                                                                                                        |
| TNM Stage Groups                     | Stage 0 \| Stage I \| Stage IA \| Stage IB \| Stage II \| Stage IIA \| Stage IIB \| Stage IIC \| Stage III \| Stage IIIA \| Stage IIIB \| Stage IIIC \| Stage IV \| Stage IVA \| Stage IVB |
| FIGO Stage                           | Stage I \| Stage IA \| Stage IB \| Stage IC \| Stage II \| Stage IIA \| Stage IIB \| Stage III \| Stage IIIA \| Stage IIIB \| Stage IIIC \| Stage IV \| Stage IVA \| Stage IVB             |
| Ann Arbor Stage                      | Stage I \| Stage II \| Stage III \| Stage IV (may include A/B suffix)                                                                                                                      |
| International Prognostic Index (IPI) | Low \| Low-Intermediate \| High-Intermediate \| High                                                                                                                                       |
| HER2 IHC Status                      | 0 \| 1+ \| 2+ \| 3+                                                                                                                                                                        |
| ER/PR IHC Status                     | Positive \| Negative \| (percentage values)                                                                                                                                                |
| Microsatellite Instability           | MSI-High \| MSI-Low \| MSS (Microsatellite Stable)                                                                                                                                         |
| MGMT Promoter Status                 | Methylated \| Unmethylated                                                                                                                                                                 |
| Platinum Sensitivity                 | Sensitive \| Resistant \| Refractory                                                                                                                                                       |
| Homologous Recombination Deficiency  | Positive \| Negative \| Deficient \| Proficient                                                                                                                                            |
| Surgery Type                         | Primary resection \| Debulking \| Biopsy only \| Mastectomy \| Lumpectomy                                                                                                                  |
| Residual Disease                     | R0 (complete resection) \| R1 (microscopic residual) \| R2 (macroscopic residual)                                                                                                          |
| Menopausal Status                    | Premenopausal \| Postmenopausal \| Perimenopausal                                                                                                                                          |
| Race                                 | White \| Black or African American \| Asian \| Native Hawaiian or Pacific Islander \| American Indian or Alaska Native \| Other \| Unknown                                                 |
| Alcohol Intake                       | Current \| Former \| Never                                                                                                                                                                 |
| COPD Stage                           | Stage 0 \| Stage I \| Stage II \| Stage III \| Stage IV                                                                                                                                    |
| End of Study Reason                  | Completed \| Death \| Disease Progression \| Adverse Event \| Withdrawal \| Lost to Follow-up                                                                                              |
| Variant Classification               | Missense\_Mutation \| Nonsense\_Mutation \| Frame\_Shift\_Del \| Frame\_Shift\_Ins \| In\_Frame\_Del \| In\_Frame\_Ins \| Splice\_Site \| Silent                                           |