> For the complete documentation index, see [llms.txt](https://docs.owkin.com/llms.txt). Markdown versions of documentation pages are available by appending `.md` to page URLs; this page is available as [Markdown](https://docs.owkin.com/connect-and-integrate/api-documentation.md).

# API documentation

**Architecture pattern.** K Pro exposes two programmable surfaces: a REST API for synchronous job submission, status polling, and result retrieval (structured JSON with provenance), and an MCP server endpoint that lets external agents discover and invoke K Pro platform directly.

Long-running work (e.g. literature mining, multi-omic queries, federated analyses) runs asynchronously through the orchestrator. Submissions return a job ID; completion may be delivered via webhook callback or polled status.

**Representative use cases.**

* **Batch target scoring.** A differential-expression pipeline submits a gene list; the orchestrator runs the target-evaluation agent over each entry and returns a ranked JSON payload with confidence and evidence links.
* **Pipeline step.** Nextflow or Snakemake stages call K Pro as a typed REST node, blocking on a webhook callback before downstream steps proceed.
* **Embedded reasoning.** A customer's own agent calls K Pro tools over MCP to compose target-evaluation reasoning into its own workflow without round-tripping data through a UI.


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